Gilbert’s syndrome is a genetic disorder with mild jaundice from time to time. It is usually harmless and does not require treatment. It is due to a reduced amount of a chemical in the liver which processes a breakdown product of blood cells, called bilirubin. It is caused by relative deficiency of glucuronyl transferase in the liver.Many anesthetic drugs metabolized in the liver through this pathway can potentially accumulate leading to adverse outcomes.
Dr Thomas , the senior anesthetist explains the issues of giving GA in such a patient who undergoes nasal surgery.
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