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There are different types of saline nasal spray available, the most common is a salt water solution packaged in a spray bottle. Saline nasal spray provides moisture to dry, irritated or plugged nasal passages. The moisture, typically a salt and water solution, helps soften and dissolve the thick mucus that blocks airflow or causes discomfort. Nasal sprays and nasal washes help the body to flush out allergens from the upper respiratory tract. Removing these proteins and allergy triggers reduces the number of allergic reactions during allergy season.